High yield acyl anion trapping reactions: direct nucleophilic acylation of isocyanates and isothiocyanates.

D Seyferth, RC Hui

Index: Seyferth, Dietmar; Hui, Richard C. Tetrahedron Letters, 1984 , vol. 25, # 46 p. 5251 - 5254

Full Text: HTML

Citation Number: 26

Abstract

Abstract The reactions of t-BuLi, sec-BuLi and n-BuLi with CO in the presence of isothiocyanates and isocyanates gives, after hydrolytic work-up, α-oxothioamides, RC (O) C (S) NHR′, and α-oxoamides, RC (O) C (O) NHR′, respectively, in good yield. Competition