Bulletin of the Korean Chemical Society

Convenient n-formylation of amines in dimethylformamide with methyl benzoate under microwave irradiation

D Yang, HB Jeon

Index: Yang, Dongsik; Jeon, Heung Bae Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 5 p. 1424 - 1426

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Citation Number: 14

Abstract

Formylation of amines is a very useful process in synthetic organic chemistry. Formamides are a class of important intermediates that have been widely used in synthesis of pharmaceutically important compounds. 1 In addition, formamides have been also extensively employed in organic synthesis as protecting group of amines, 2 precursor for formamidines3 and isocyanide4 preparation, an intermediate for mono methylated amines ...

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