Beilstein journal of organic chemistry

Synthesis of SF5-containing benzisoxazoles, quinolines, and quinazolines by the Davis reaction of nitro-(pentafluorosulfanyl) benzenes

P Beier, T Pastýříková

Index: Beier, Petr; Pastyrikova, Tereza Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 411 - 416

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Citation Number: 17

Abstract

Abstract Meta-or para-nitro-(pentafluorosulfonyl) benzenes underwent the Davis reaction with arylacetonitriles to provide the SF 5-containing benzisoxazoles. Good yields were obtained with arylacetonitriles containing the electron-neutral or electron-donor group, while those with the electron-acceptor group were found to be unreactive. Reductions of the benzisoxazoles gave ortho-aminobenzophenones in high yields. Their synthetic utility ...