Alternative synthesis of dibenzo-and dipyrido-[1, 3] diazepines from thioamides and o, o′-diaminobiaryls

K Matsuda, I Yanagisawa, Y Isomura…

Index: Matsuda, Koyo; Yanagisawa, Isao; Isomura, Yasuo; Mase, Toshiyasu; Shibanuma, Tadao Synthetic Communications, 1997 , vol. 27, # 14 p. 2393 - 2402

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Citation Number: 16

Abstract

Yamanouchi Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co. Ltd., 21 Miyukigaoka, Tsukuba, Ibaraki, 305 JAPAN ... Abstract: Thioamides were treated with iodomethane, and then o,o'- diaminobiphenyl or bipyridyl to afford 6-substituted-5H-dibenzo- or dipyrido [ 1,3]diazepines in good yields. ... Dibenzo- and dipyrido[ 1,3]diazepines are of pharmaceutical interest, and ... Dipyrido[ 1,3]diazepines have been reported to have activities on central ...

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