Degradation of Tetrahydro-β-carbolines in the Presence of Nitrite: HPLC-MS Analysis of the Reaction Products

S Diem, B Gutsche, M Herderich

Index: Diem, Stefanie; Gutsche, Birgit; Herderich, Markus Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 12 p. 5993 - 5998

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Citation Number: 6

Abstract

Motivated by the identification of numerous novel tetrahydro-β-carboline-carboxylic acids in food samples, we studied the reactions of tetrahydro-β-carbolines in the presence of nitrosating agents. The anticipated formation of nitroso derivatives from unsubstituted tetrahydro-β-carbolines, and from tetrahydro-β-carboline-3-carboxylic acids was indicated by HPLC-MS/MS analysis and validated by the characteristic product ion spectra of the ...

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