Potent oxindole based human β 3 adrenergic receptor agonists

…, CA Droste, ML Heiman, A Kriauciunas, DJ Sall…

Index: Stevens, F. Craig; Bloomquist, William E.; Borel, Anthony G.; Cohen, Marlene L.; Droste, Christine A.; Heiman, Mark L.; Kriauciunas, Aidas; Sall, Daniel J.; Tinsley, Frank C.; Jesudason, Cynthia D. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 22 p. 6270 - 6273

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Citation Number: 24

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The synthesis and biological evaluation of a series of oxindole β 3 adrenergic receptor agonists is described. A modulation of rat atrial tachycardia was observed with substitution at the 3-position of the oxindole moiety. ... The synthesis and biological evaluation of a series of oxindole ...