ZnO-mediated regioselective C-arylsulfonylation of indoles: a facile solvent-free synthesis of 2-and 3-sulfonylindoles and preliminary evaluation of their activity against …

G Tocco, M Begala, F Esposito, P Caboni, V Cannas…

Index: Tocco, Graziella; Begala, Michela; Esposito, Francesca; Caboni, Pierluigi; Cannas, Valeria; Tramontano, Enzo Tetrahedron Letters, 2013 , vol. 54, # 46 p. 6237 - 6241

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Abstract

Abstract A ZnO-mediated one-pot solvent-free protocol for the regioselective C- arylsulfonylation of indoles is described and some novel derivatives were tested on wild type and non-nucleoside inhibitor resistant K103N and Y181C HIV-1 reverse transcriptases (RTs).

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