Diastereoselective Synthesis of Five??and Seven??Membered Rings by [2+ 2+ 1],[3+ 2],[3+ 2+ 2], and [4+ 3] Carbocyclization Reactions of β??Substituted (Alkenyl)( …

J Barluenga, J Alonso…

Index: Barluenga, Jose; Alonso, Jorge; Fananas, Francisco J. Chemistry - A European Journal, 2005 , vol. 11, # 17 p. 4995 - 5006

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Citation Number: 11

Abstract

Abstract β-Substituted alkenylcarbene complexes react with methyl ketone lithium enolates to give different carbocyclization products depending on the structure of the lithium enolate, on the metal of the carbene complex, and on the reaction media. Thus, the reactions of aryl and alkyl methyl ketone lithium enolates with β-substituted alkenyl chromium and tungsten carbene complexes in diethyl ether afford 1, 3-cyclopentanediol derivatives derived from a ...