Palladium??Catalyzed Sonogashira Coupling of Aryl Mesylates and Tosylates

PY Choy, WK Chow, CM So, CP Lau…

Index: Choy, Pui Ying; Chow, Wing Kin; So, Chau Ming; Lau, Chak Po; Kwong, Fuk Yee Chemistry - A European Journal, 2010 , vol. 16, # 33 p. 9982 - 9985

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Citation Number: 32

Abstract

Aryl alkynes are important synthetic precursors and subunits for a range of pharmaceutically attractive and valued materials science organic compounds.[1] One of the most straightforward and versatile protocols for the construction of Csp2ÀCsp bond is the palladium-catalyzed cross-coupling of aryl halides/sulfonates and terminal alkynes, namely, Sonogashira coupling.[2] This methodology features a modular approach to assemble an ...

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