Synlett

Synthesis of ceramide mimics with a pseudo cyclic framework

H Suzuki, M Mori, M Shibakami

Index: Suzuki, Hikokazu; Mori, Michiko; Shibakami, Motonari Synlett, 2003 , # 14 p. 2163 - 2166

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Citation Number: 9

Abstract

Abstract We have designed and synthesized ceramide mimics with a pseudo cyclic framework that can be converted to 'dimeric'sphingomyelins and glycosphingolipids for potential components of artificial rafts. These molecules are characterized by the presence of (i) two hydrophilic head groups,(ii) a covalently bonded hydrocarbon chain, and (iii) two untethered alkyl chains. Self-assembling of a ceramide mimic into nanorods is briefly ...