Nucleosides and Nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl) pyrimidines: Synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, …

A Matsuda, K Takenuki, T Sasaki…

Index: Matsuda; Takenuki; Sasaki; Ueda Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 234 - 239

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Citation Number: 73

Abstract

Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060, Japan, and Cancer Research Institute, Kanazawa University, Takara-machi, Kanazawa 920, Japan. Received April 24, 19%(2's and 2'R)-2'-Deoxy-2'-C-methylcytidme (li and 15) and (2'S)-2'-deoxy-2'-C-ethylcytidine (lj) have been synthesized from the corresponding 2'-C- alkylarabinofuranosyl-or-ribofuranosylpyrimidine derivatives 3 and 4 by radical ...