The Synthesis of Desoxycarpyrinic and Carpyrinic Acids

H Rapoport, EJ Volcheck Jr

Index: Rapoport; Volcheck Journal of the American Chemical Society, 1956 , vol. 78, p. 2451,2453

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Citation Number: 18

Abstract

Desoxycarpyrinic arid and carpyrinic acid, degradation products of carpaine, have been synthesized by application of the Hammick reaction (decarboxylation of a picolinic acid in the presence of a carbonyl compound) to the half-ester aldehyde of suberic acid. The intermediate carbinol group in the one case was converted to the chloride and thence reduced to methylene, while in the other case it was oxidized to the ketone and then ...