Mesyl azide: A superior reagent for diazo transfer

…, RE Ruckle Jr, MJ Hennessy

Index: Taber, Douglass F.; Ruckle, Robert E.; Hennessy, Michael J. Journal of Organic Chemistry, 1986 , vol. 51, # 21 p. 4077 - 4078

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Citation Number: 158

Abstract

Base-catalyzed transfer of the diazo moiety to a methylene group adjacent to one or more electron-withdrawing groups is a well established and powerful synthetic tooL2 The most commonly used reagent for diazo transfer has been p-toluenesulfonyl (tosyl) azide, 3 although isolated incidences of diazo transfer to@-dicarbonyl systems by other reagents have been rep~ rted.~~~ Difficulties have been reported in the chromatographic ...