Tetrahedron

Synthesis of 17β-estradiol derivatives with N-butyl, N-methyl alkylamide side chain at position 15

D Poirier, Y Mérand, F Labrie

Index: Poirier, Donald; Merand, Yves; Labrie, Fernand Tetrahedron, 1991 , vol. 47, # 37 p. 7751 - 7766

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Citation Number: 22

Abstract

New derivatives of 17β-estradiol with N-butyl, N-methyl alkylamide side chains of three different lengths at position 15 have been synthesized from estrone. Compounds 5 and 6 having a shorter alkylamide chain were obtained in eleven steps by introduction of a 15, ...