Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy

SJ O'Connor, KJ Barr, L Wang…

Index: Journal of Medicinal Chemistry, , vol. 42, # 18 p. 3701 - 3710

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Citation Number: 40

Abstract

... Journal of Medicinal Chemistry. ... Tampa, Florida 33612. J. Med. Chem. , 1999, 42 (18), pp 3701–3710. DOI: 10.1021/jm9901935. Publication Date (Web): August 25, 1999. Copyright © 1999 American Chemical Society. ...

Synthesis of new thiazole-2,-4, and-5-yl-(amino) methylphosphonates and phosphinates: unprecedented cleavage of thiazole-2 derivatives under acidic conditions

[Tetrahedron, , vol. 66, # 45 p. 8661 - 8666]

Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy

Abstract

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