Tetrahedron letters

The use of silyl enol ethers in the alkylation of substituted cyclanones

P Angers, P Canonne

Index: Angers, Paul; Canonne, Persephone Tetrahedron Letters, 1994 , vol. 35, # 3 p. 367 - 370

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Citation Number: 14

Abstract

Abstract The reactions of 1-(trimethylsiloxy)-3-methylcyclopent-1-ene, 1-(trimethylsiloxy)-3- methylcyclohex-1-ene and 1-(trimethylsiloxy)-3, 3-dimethylcyclohex-1-ene with various alkylating agents in the presence of silver trifluoroacetate produced the corresponding 2, 3- dialkylated and 2, 3, 3-trialkylated cyclanones with high regiodifferentiation and stereoselection.