First enantioselective total synthesis of penicimarin B, aspergillumarins A and B

JS Yadav, AK Mishra, SS Dachavaram, SG Kumar…

Index: Yadav, Jhillu Singh; Mishra, Anand Kumar; Dachavaram, Soma Shekar; Ganesh Kumar; Das, Saibal Tetrahedron Letters, 2014 , vol. 55, # 18 p. 2921 - 2923

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Abstract

Abstract A convergent enantioselective synthesis of penicimarin B, aspergillumarin A and B has been reported using Brown's allylation, DeBrabander–Bhattacharjee lactonization and Grubbs cross coupling metathesis. During this synthesis we have standardized the conditions for DeBrabande–Bhattacharjee lactonization to obtain excellent yield (> 90%).

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