Chemistry Letters

Substitution of alkyl and hydroxyalkyl group for ring hydrogen and of hydroxyalkyl group for cyano group in gamma-irradiation of pyridinecarbonitriles in alcohol

A Sugimori, S Mori, K Maeda, M Nishijima

Index: Sugimori, Akira; Mori, Shoji; Maeda, Kazuo; Nishijima, Masayuki Chemistry Letters, 1984 , p. 769 - 772

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Abstract

Gamma-irradiation of pyridinecarbonitriles in alcohol in the presence of sulfuric acid brings about the substitution of the alkyl group derived from alcohol for the ring hydrogen, while that in the absence of sulfuric acid causes the substitution of hydroxy-alkyl group for CN at the 2- and 4-positions. Hydroxyalkyl radicals and solvated electrons play important role in the substitution.

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