Synthesis of 2H??and 13C??labelled sunitinib and its primary metabolite

PW Elsinghorst, M Gütschow

Index: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365

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Citation Number: 6

Abstract

... Journal of Labelled Compounds and Radiopharmaceuticals. ... N-Alkylation, eg N-d 5 -ethylation, has been used to stable label a variety of drugs to obtain internal ... A concise five-step synthesis was developed to obtain either 13 C- or 2 H-labelled sunitinib (SU11248) or its primary ...