Synlett

Synthesis of O-Ethyl Thioformate: A Useful Reagent for the Thioformylation of Amines

CJ Borths, J Chan, BJ Burke, RD Larsen

Index: Borths, Christopher J.; Chan, Johann; Burke, Brenda J.; Larsen, Robert D. Synlett, 2009 , # 19 p. 3139 - 3142

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Citation Number: 2

Abstract

Abstract O-Ethyl thioformate has been synthesized from triethylorthoformate and hydrogen sulfide gas using a Brønstead acid catalyst. The product can be isolated as a neat liquid in 83% overall yield. Both the crude and purified thiolate can be used to thioformylate a ...