Journal of the American Chemical Society

DDQ-mediated direct cross-dehydrogenative-coupling (CDC) between benzyl ethers and simple ketones

Y Zhang, CJ Li

Index: Zhang, Yuhua; Li, Chao-Jun Journal of the American Chemical Society, 2006 , vol. 128, # 13 p. 4242 - 4243

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Citation Number: 252

Abstract

A direct Cross-Dehydrogenative-Coupling (CDC) between benzyl ethers and simple ketones was developed without using any metal catalyst. By using DDQ, various benzyl ethers and simples ketones were coupled together directly to form β-alkoxyl ketones efficiently. A mechanism in which the DDQ serves the double roles of an oxidizing agent and an organomediator was proposed.

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