Journal of fluorine chemistry

Synthesis of aminophenyl and methoxyphenyl perfluoroalkyl ketones

H Lee, A Czarny, MA Battiste, L Strekowski

Index: Lee, Hyeran; Czarny, Agnieszka; Battiste, Merle A.; Strekowski, Lucjan Journal of Fluorine Chemistry, 1998 , vol. 91, # 2 p. 221 - 224

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Citation Number: 11

Abstract

The title compounds are obtained by direct hydrolysis of the corresponding 2/4- perfluoroalkyl-substituted anilines and anisoles by the system AcOH/HBr/H2O/Al2O3. A two- step preparation of 2/4-perfluoroacylanilines involves the treatment of the 2/4- perfluoroalkylaniline with sodium ethoxide followed by hydrolysis of the resultant diethyl acetal with hydriodic acid.