Tetrahedron letters

A new and convenient in-situ method of generating phenyl isocyanates from anilines using oxalyl chloride

LM Oh, PG Spoors, RM Goodman

Index: Oh, Lynette M.; Spoors, P. Grant; Goodman, Richard M. Tetrahedron Letters, 2004 , vol. 45, # 24 p. 4769 - 4771

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Citation Number: 8

Abstract

A new and convenient method of generating phenyl isocyanates from anilines using oxalyl chloride is described. Acylation of a variety of substituted aniline hydrochlorides with oxalyl chloride affords the intermediate oxamic chlorides, which smoothly undergo thermal decomposition to the corresponding isocyanates.

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