Synthesis, structural and spectral properties of Au complexes: luminescence properties and their non-covalent DNA binding studies

…, I Camacho-Arroyo, A González-Arenas…

Index: Huerta-Aguilar, Carlos; Talamantes Gomez, Jose M.; Thangarasu, Pandiyan; Camacho-Arroyo, Ignacio; Gonzalez-Arenas, Aliesha; Narayanan, Jayanthi; Srivastava, Rajendra Applied Organometallic Chemistry, 2013 , vol. 27, # 10 p. 578 - 587

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Abstract

Development of metal-based drugs has prospered consistently since the discovery of cisplatin, cis-[Pt (NH3) 2Cl2], as basic chemotherapeutics [1, 2] because the adduct formation of cisplatin with DNA triggers apoptosis (therapeutic effect).[3] Along with cisplatin, other platinum (II) drugs, such as carboplatin and oxaliplatin, also continue to play a central role in the treatment of cancer and are used in chemotherapeutic regimes of around half of ...

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