Aminooxy derivatives. IV. Antimicrobial activity of some O-ethers of 4, 6-diamino-1, 2-dihydro-1-hydroxy-2-substituted 1, 3, 5-triazines

P Mamalis, L Jeffries, SA Price, MJ Rix…

Index: Mamalis,P. et al. Journal of Medicinal Chemistry, 1965 , vol. 8, p. 684 - 691

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Citation Number: 17

Abstract

Some new 0-ethers of 4, 6-dianiino-1, 2-dihydro-lh~ dro~ y-~-subst~ itu~ ed 1, 3, 5-trinzines have been prepared. The antibacterial properties of these compounds and of some previously prepared analogs are described. In vitro activity was observed against a wide range of bacteria; a number of compounds inhibited the growth of Candida albicans. Variation of substituents in the I-position resulted in compounds with essentially ...

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