Biochemistry

Cytidylyl and uridylyl cyclase activity of Bacillus anthracis edema factor and Bordetella pertussis CyaA

…, S Dove, F Kees, J Schlossmann, J Geduhn…

Index: Goettle, Martin; Dove, Stefan; Kees, Frieder; Schlossmann, Jens; Geduhn, Jens; Koenig, Burkhard; Shen, Yuequan; Tang, Wei-Jen; Kaever, Volkhard; Seifert, Roland Biochemistry, 2010 , vol. 49, # 26 p. 5494 - 5503

Full Text: HTML

Citation Number: 41

Abstract

Cyclic adenosine 3′, 5′-monophosphate (cAMP) and cyclic guanosine 3′, 5′- monophosphate (cGMP) are second messengers for numerous mammalian cell functions. The natural occurrence and synthesis of a third cyclic nucleotide (cNMP), cyclic cytidine 3′, 5′-monophosphate (cCMP), is a matter of controversy, and almost nothing is known about cyclic uridine 3′, 5′-monophosphate (cUMP). Bacillus anthracis and Bordetella ...