Synthesis and spectroscopic characterization of model compounds for the active site cofactor in copper amine oxidases

M Mure, JP Klinman

Index: Mure, Minae; Klinman, Judith P. Journal of the American Chemical Society, 1993 , vol. 115, # 16 p. 7117 - 7127

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Citation Number: 129

Abstract

Abstract: The synthesis and spectroscopic characterization of compounds which model different forms of the active site cofactor in copper amine oxidases have been pursued. As described, 5-(2, 4, 5-trihydroxybenzyl) hydantoin (lrdH3), its corresponding quinone (loxH), and 6-amino-4-ethylresorcinol (7H2) have been prepared. Additionally, 5-(3, 4- dihydroxybenzyl) hydantoin (2, dHz) was synthesized for comparative purposes. ...