Haloacetylated enol ethers: 4 [6]. Synthesis of 4??trihalomethyl??2??methylthiopyrimidines

…, EÍL Clerici, AP Marcos

Index: Madruga, Claudia da C.; Clerici, Edflia; Martins, Marcos A. P.; Zanatta, Nilo Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 735 - 738

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Citation Number: 54

Abstract

Abstract The synthesis of a series of 5-and 6-substituted 4-trihalomethyl-2- methylthiopyrimidines, prepared from the cyclocondensation reaction of β-alkoxyvinyl tri [fluoro] chloromethyl ketones with 2-methyl-2-thiopseudourea sulfate, are reported. A systematic study to find the best reaction conditions were carried out.