The use of dipole moments in the conformational analysis of nicotinic acid derivatives

J Kuthan, L Musil, V Jehlička

Index: Kuthan,J. et al. Collection of Czechoslovak Chemical Communications, 1977 , vol. 42, p. 283 - 291

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Citation Number: 19

Abstract

Apparent dipole moments in benzene of the compounds II-VII, together with the theoretical moments of their CNDOj2 models, can be employed in a semiquantitative estimate of conformational population in methyl nicotinate (II) and nicotinamide (Ill). In the case of nicotinic acid (1) this approach does not lead to unequivocal conclusions.