Synthesis

A novel and efficient synthesis of dihydrexidine

JP Cueva, DE Nichols

Index: Cueva, Juan Pablo; Nichols, David E. Synthesis, 2009 , # 5 p. 715 - 720

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Citation Number: 3

Abstract

Abstract An efficient synthesis of the dopamine D 1 selective full agonist dihydrexidine has been achieved in high yields and requiring no chromatographic separations via a facilitated intramolecular Henry cyclization of a (nitropropyl) benzophenone and subsequent diastereomerically selective reduction of the resulting tricyclic nitroalkene.