Potential antidepressants: 2-(Phenylthio) aralkylamines

J Jílek, J Urban, P Taufmann, J Holubek…

Index: Jilek, Jiri; Urban, Jiri; Taufmann, Petr; Holubek, Jiri; Dlabac, Antonin; et al. Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 7 p. 1995 - 2008

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Citation Number: 7

Abstract

Abstract Reactions of 2-(phenylthio) benzyl chloride with dimethylamine, diethylamine, pyrrolidine, piperidine, morpholine, and 1-methylpiperazine afforded the title compounds VI- XI. Reaction of 2-(phenylthio) benzaldehyde with nitromethane gave the nitrostyrene XIV which was reduced with lithium aluminium hydride to 2-(2-(phenylthio) phenyl) ethylamine (XVI). This was transformed to the N-methyl and N, N-dimethyl derivatives XVIII and XIX. ...