Tetrahedron

RuCl 2 (DMSO) 4 catalyzes the β-alkylation of secondary alcohols with primary alcohols through a hydrogen autotransfer process

R Martínez, DJ Ramón, M Yus

Index: Martinez, Ricardo; Ramon, Diego J.; Yus, Miguel Tetrahedron, 2006 , vol. 62, # 38 p. 8982 - 8987

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Citation Number: 124

Abstract

The electrophilic β-alkylation of secondary alcohols with primary alcohols is accomplished by a hydrogen autotransfer process catalyzed by RuCl2 (DMSO) 4. The reaction can produce either simple alkylated secondary alcohols or α, β-unsaturated ketones with good to excellent results just by choosing the appropriate starting secondary alcohol (methyl or longer chain secondary alcohol, respectively), as well as quinolines (by using 2- ...

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