Formal Homologous Aldol Reactions: Interrupting the Nazarov Cyclization via Carboalkoxylation of Alkynes

YK Wu, FG West

Index: Bonderoff, Sara A.; Grant, Tina N.; West; Tremblay, Martin Organic Letters, 2013 , vol. 15, # 11 p. 2888 - 2891

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Citation Number: 16

Abstract

Reactions between 1, 4-pentadien-3-ones and aryl acetylenes in the presence of BF3· OEt2 furnish α-phenacyl cyclopentanones via a domino electrocyclization/carboalkoxylation reaction sequence. The overall process underscores a new mode of interrupted Nazarov