Analogues of the neuroleptic agent isobutaclamol: Stereoisomeric 3b, 4, 5, 6, 7, 9, 9a, 10-octahydro-[1] benzothiepino [2, 3, 4-ed] pyrido [2, 1-a] isoquinolin-5-ols and …

…, E Svátek, A Dlabač, M Valchář, M Protiva

Index: Protiva; Jilek Collection of Czechoslovak Chemical Communications, 1951 , vol. 16/17, p. 151

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Abstract

Abstract 10, 11-Dihydrodibenzo [b, f] thiepin-10-carbonitrile (XVI) was reduced with aluminium hydride to the primary amine XVII which was formylated with acetic formic anhydride. The formamide derivative was cyclized by the Bischler-Napieralski reaction to the