Investigating biological activity spectrum for novel quinoline analogues

R Musiol, J Jampilek, K Kralova, DR Richardson…

Index: Musiol, Robert; Jampilek, Josef; Kralova, Katarina; Richardson, Des R.; Kalinowski, Danuta; Podeszwa, Barbara; Finster, Jacek; Niedbala, Halina; Palka, Anna; Polanski, Jaroslaw Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 3 p. 1280 - 1288

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Citation Number: 111

Abstract

The lack of the wide spectrum of biological data is an important obstacle preventing the efficient molecular design. Quinoline derivatives are known to exhibit a variety of biological effects. In the current publication, we tested a series of novel quinoline analogues for their photosynthesis-inhibiting activity (the inhibition of photosynthetic electron transport in spinach chloroplasts (Spinacia oleracea L.) and the reduction of chlorophyll content in ...