Tetrahedron Letters

Microwave assisted synthesis of triazolobenzoxazepine and triazolobenzoxazocine heterocycles

A Ellison, R Boyer, P Hoogestraat, M Bell

Index: Ellison, Aubrey; Boyer, Robert; Hoogestraat, Paul; Bell, Michael Tetrahedron Letters, 2013 , vol. 54, # 45 p. 6005 - 6007

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Citation Number: 5

Abstract

Abstract Intramolecular click chemistry was utilized to effect synthesis of the benzofused, triazole ring systems. The trimethylsilyl group was found to impede the reaction progress, and therefore, conditions employing in situ removal of the TMS group coupled with microwave irradiation give the penultimate targets with good conversion.

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