Organocatalytic Chemoselective Monoacylation of 1, n??Linear Diols

K Yoshida, T Furuta, T Kawabata

Index: Yoshida, Keisuke; Furuta, Takumi; Kawabata, Takeo Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4888 - 4892

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Citation Number: 20

Abstract

Selective monoacylation of 1, n-linear diols seems to be a simple molecular transformation, however, it is still a challenging subject in current organic synthesis because overacylation is usually unavoidable. High reactivity of primary hydroxy groups at the both ends of the linear diols makes selective monoacylation difficult. Since the steric environments of the free OH groups in diol 1 are similar to those of a free OH in 2 (Scheme1), the strategy for ...

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