Water??Soluble Chiral Ruthenium (II) Phenyloxazoline Complex: Reusable and Highly Enantioselective Catalyst for Intramolecular Cyclopropanation Reactions
AM Abu??Elfotoh, DPT Nguyen…
Index: Abu-Elfotoh, Abdel-Moneim; Nguyen, Diem Phuong Thi; Chanthamath, Soda; Phomkeona, Kesiny; Shibatomi, Kazutaka; Iwasa, Seiji Advanced Synthesis and Catalysis, 2012 , vol. 354, # 18 p. 3435 - 3439
Full Text: HTML
Citation Number: 13
Abstract
Abstract The intramolecular cyclopropanation of various trans-allylic diazoacetates and alkenyl diazoketones has been achieved with excellent enantioselectivities of up to 98% ee and in quantitative yields by using a water-soluble ruthenium (II)/hydroxymethyl (phenyl) oxazoline catalyst in a water/ether biphasic medium. The catalyst could be reused at least five times.
Related Articles:
[Doyle, Michael P.; Austin, Richard E.; Bailey, A. Scott; Dwyer, Michael P.; Dyatkin, Alexey B.; Kalinin, Alexey V.; Kwan, Michelle M. Y.; Liras, Spiros; Oalmann, Christopher J.; Pieters, Roland J.; Protopopova, Marina N.; Raab, Conrad E.; Roos, Gregory H. P.; Zhou, Qi-Lin; Martin, Stephen F. Journal of the American Chemical Society, 1995 , vol. 117, # 21 p. 5763 - 5775]
[Doyle, Michael P.; Austin, Richard E.; Bailey, A. Scott; Dwyer, Michael P.; Dyatkin, Alexey B.; Kalinin, Alexey V.; Kwan, Michelle M. Y.; Liras, Spiros; Oalmann, Christopher J.; Pieters, Roland J.; Protopopova, Marina N.; Raab, Conrad E.; Roos, Gregory H. P.; Zhou, Qi-Lin; Martin, Stephen F. Journal of the American Chemical Society, 1995 , vol. 117, # 21 p. 5763 - 5775]
[Doyle, Michael P.; Austin, Richard E.; Bailey, A. Scott; Dwyer, Michael P.; Dyatkin, Alexey B.; Kalinin, Alexey V.; Kwan, Michelle M. Y.; Liras, Spiros; Oalmann, Christopher J.; Pieters, Roland J.; Protopopova, Marina N.; Raab, Conrad E.; Roos, Gregory H. P.; Zhou, Qi-Lin; Martin, Stephen F. Journal of the American Chemical Society, 1995 , vol. 117, # 21 p. 5763 - 5775]