Rapid microwave-assisted synthesis of phenyl ethers under mildly basic and nonaqueous conditions

J Sarju, TN Danks, G Wagner

Index: Sarju, Julien; Danks, Timothy N.; Wagner, Gabriele Tetrahedron Letters, 2004 , vol. 45, # 41 p. 7675 - 7677

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Citation Number: 32

Abstract

A mild method for O-alkylation of phenols has been developed using stoichiometric amounts of K2CO3 as a base and microwave irradiation. The method is suitable for substrates that are sensitive towards strong bases or hydrolysis, or difficult to extract from an aqueous medium.