Mechanistic and stereochemical aspects of the 1, 2–3, 4 hydride reduction of enones

RB Gammill, SA Nash, LT Bell, W Watt, SA Mizsak…

Index: Gammill, Ronald B.; Nash, Sharon A.; Bell, Larry T.; Watt, William; Mizsak, Stephen A.; et al. Tetrahedron Letters, 1990 , vol. 31, # 37 p. 5303 - 5306

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Citation Number: 3

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A unique mode of metal hydride reduction of unsaturated ketones is described which proceeds with a high degree of regio- and stereocontrol. ... LiAlH 4 or Red-Al® reduction of α,β-unsaturated ketones can proceed via a 1,2–3,4 mode of reduction. In certain cases up to three ...