Ni??Catalyzed Reductive Allylation of Unactivated Alkyl Halides with Allylic Carbonates

…, F Wu, Z Zang, H You, H Gong

Index: Dai, Yijing; Wu, Fan; Zang, Zhenhua; You, Hengzhi; Gong, Hegui Chemistry - A European Journal, 2012 , vol. 18, # 3 p. 808 - 812

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Citation Number: 51

Abstract

Allylation of alkyl substrates represents a very important reaction type in modern synthetic organic chemistry. Numerous elegant approaches to allylated alkanes have been developed, primarily based on the transition-metal-catalyzed addition of alkyl nucleophiles to allylic electrophiles.[1–3] This includes the recent Ni-catalyzed asymmetric Negishi coupling of primary alkylzinc reagents with allylic chlorides developed by Fu and co- ...