Penoxsulam—Structure–activity relationships of triazolopyrimidine sulfonamides

TC Johnson, TP Martin, RK Mann…

Index: Johnson, Timothy C.; Martin, Timothy P.; Mann, Richard K.; Pobanz, Mark A. Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 12 p. 4230 - 4240

Full Text: HTML

Citation Number: 30

Abstract

The discovery of the sulfonamide herbicides, which inhibit the enzyme acetolactate synthase (ALS), has resulted in many investigations to exploit their herbicidal activity. One area which proved particularly productive was the N-aryltriazolo [1, 5-c] pyrimidine sulfonamides, providing three commercial herbicides, cloransulam-methyl, diclosulam and florasulam. Additional structure–activity investigations by reversing the sulfonamide linkage resulted ...