Tetrahedron letters

A novel linker strategy for solid-phase synthesis

JR Morphy, Z Rankovic, DC Rees

Index: Morphy, J. Richard; Rankovic, Zoran; Rees, David C. Tetrahedron Letters, 1996 , vol. 37, # 18 p. 3209 - 3212

Full Text: HTML

Citation Number: 112

Abstract

The REM resin for solid phase synthesis is described. Its use is illustrated by preparing a small array of tertiary amines using a Hofmann elimination reaction. No functional group is required for linking these compounds onto the resin other than the amine constructed during the synthesis.

Related Articles:

Reagent concentration effects in the REM resin solid phase synthesis of tertiary amines

[Morphy, J. Richard; Rankovic, Zoran; York, Mark Tetrahedron, 2003 , vol. 59, # 12 p. 2137 - 2145]

The synthesis of some alcohols derived from 1, 2, 3, 4-tetrahydroisoquinoline and from 1, 2, 3, 4-tetrahydroquinoline

[Ferles, Miloslav; Silhankova, Alexandra; Kafka, Stanislav; Taufmann, Petr; Motacek, Tomas Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # l p. 1759 - 1764]

Silyl modification of biologically active compounds

[Lukevics; Germane; Segal; Zablotskaya Chemistry of Heterocyclic Compounds, 1997 , vol. 33, # 2 p. 234 - 238]

More Articles...