Studies on regioselectivity of nitration of coumarins with cerium (IV) ammonium nitrate: Solid-state nitration of 6-hydroxy-coumarins on montmorillonite K-10 clay …

…, M Datta, P De, R Chakravarty

Index: Ganguly, Nemai C.; Datta, Mrityunjoy; De, Prithwiraj; Chakravarty, Romaprosad Synthetic Communications, 2003 , vol. 33, # 4 p. 647 - 659

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Citation Number: 21

Abstract

Abstract 6-Hydroxycoumarins and their O-methyl ethers were selectively nitrated in the carbocyclic ring even in the presence of activating 4-Me group in the 2-pyrone ring with cerium (IV) ammonium nitrate (CAN) in acetic acid and acetonitrile in acceptable-to- excellent yields. Acetonitrile was found to be a better solvent for regioselective nitration than acetic acid. Use of CAN on montmorillonite K-10 clay under microwave irradiation for ...