A New and Effective Synthetic Method for the Preparation of the Esters, Peptides, and Lactones Using 3-(5-Nitro-2-oxo-1, 2-dihydro-1-pyridyl)-1, 2-benzisothiazole 1, 1 …

A Ahmed, N Taniguchi, H Fukuda, H Kinoshita…

Index: Ahmed, Alauddin; Taniguchi, Nagahiro; Fukuda, Hirohiko; Kinoshita, Hideki; Inomata, Katsuhiko; Kotake, Hiroshi Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 3 p. 781 - 786

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Citation Number: 23

Abstract

3-(5-Nitro-2-oxo-1, 2-dihydro-1-pyridyl)-1, 2-benzisothiazole 1, 1-dioxide (BID-NPy), readily prepared from 3-chloro-1, 2-benzisothiazole 1, 1-dioxide and 5-nitro-2-pyridone, proved to be a very useful condensing reagent. A variety of esters, dipeptides, and lactones were obtained in excellent yields. Furthermore, BID-NPy was successfully employed for the lactonization step in a new synthesis of a naturally occurring (±)-(E)-8-dodecen-11-olide, ...