Furopyridines. IX. Syntheses and properties of 3??ethoxy derivatives of furo [2, 3??b]??, furo [3, 2??b]??, furo [2, 3??c]??and furo [3, 2??c] pyridine

S Shiotani, H Morita, T Ishida…

Index: Shiotani, Shunsaku; Morita, Hiroyuki; Ishida, Toshimasa; In, Yasuko Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1205 - 1213

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Citation Number: 8

Abstract

Abstract Reaction of ethyl 3-ethoxycarbonylmethoxyfuropyridine-2-carboxylates 2a-2d with sodium ethoxide afforded 3-ethoxy derivatives 3a-3d which converted to 3- ethoxyfuropyridines 5a-5d by hydrolysis and decarboxylation of the ester group. Vilsmeier reaction of 5a and 5b gave 2-formyl-3-ethoxy derivatives 6a and 6b and 2-formyl-3-chloro derivatives 7a and 7b, while 5c and 5d did not give any formyl compound. Bromination of ...