Tetrahedron letters

Aziridination of alkenes with N-substituted hydrazines mediated by iodobenzene diacetate

J Li, JL Liang, PWH Chan, CM Che

Index: Li, Jiayin; Liang, Jiang-Lin; Chan, Philip Wai Hong; Che, Chi-Ming Tetrahedron Letters, 2004 , vol. 45, # 12 p. 2685 - 2688

Full Text: HTML

Citation Number: 65

Abstract

Aziridination of a variety of alkenes with N-substituted hydrazines mediated by iodobenzene diacetate under mild conditions (K2CO3, CH2Cl2) and ambient temperature were achieved in good to excellent yields (up to 99%), and conversions. The practicality and simplicity of this C–N bond formation protocol was exemplified by its application to the aziridination of cholesteryl acetate in a stereoselective manner.