Tetrahedron

Electrochemical heterocyclization of o-toluenesulfonamides to 3-alkyl-4, 5-dihydro-1, 2, 4-benzothiazepine-1, 1-dioxides

G Palmisano, B Danieli, G Lesma, G Fiori

Index: Palmisano, Giovanni; Danieli, Bruno; Lesma, Giordano; Fiori, Giorgio Tetrahedron, 1988 , vol. 44, # 5 p. 1545 - 1552

Full Text: HTML

Citation Number: 8

Abstract

Controlled potential oxidation of a variety of substituted o-to-luenesulfonamides at a Pt anode in MeCN using a divided cell provides 3-methyl-4, 5-dihydro-1, 2, 4- benzothiadiazepine-1, 1-dioxides selectively and in generally good yields. The scope and limitations of this one-step heterocyclization sequence are also discussed.