A new method for the radical deoxygenation of tertiary alcohols

DHR Barton, D Crich

Index: Barton, Derek H. R.; Crich, David Journal of the Chemical Society, Chemical Communications, 1984 , # 12 p. 774 - 775

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Abstract

The deoxygenation of secondary alcohols' by a radical chain reaction using tin hydrides has become commonplace.2 It is an especially useful reaction for complex natural products.3 At higher temperatures primary alcohols are also deoxygenated.4 Two methods for the radical deoxygenation of tertiary alcohols have been reported. The first involves the tin hydride reduction of phenylselenocarbonates5 and involves the chloro- carbonate of the tertiary alcohol as intermediate. The second ...