Tetrahedron

A direct method for the synthesis of polyfunctionalized unsaturated carbonyl derivatives by Michael addition of nitroalkanes to enediones with the help of DBU

R Ballini, G Bosica

Index: Ballini, Roberto; Bosica, Giovanna Tetrahedron, 1995 , vol. 51, # 14 p. 4213 - 4222

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Citation Number: 56

Abstract

The Michael addition of several nitroalkanes to dimethyl maleate,(Z)-3-hexene-2, 5-dione, N- ethyl maleimide, and N-phenyl maleimide, in MeCN or THF, proceeds very efficiently on DBU as base, and furnishes good to high yields of polyfunctionalized unsaturated carbonyl derivatives.